While obesity confers serious health concerns and increased all-cause mortality, the vast majority of deaths are due to cardiovascular causes such as ischemic heart disease and stroke. Researcher prospectively followed 208 overweight or obese patients (BMI ?25 kg/m2) receiving medical/dietary (48 percent) or bariatric surgical (52 percent) weight loss treatment during a period of approximately one year. They measured plasma metabolic parameters and vascular endothelial function using ultrasound at baseline and following weight loss intervention, and stratified analyses by median plasma insulin levels. They found that individuals with higher baseline plasma insulin levels (above median >12 uIU/ml), who had greater than 10 percent weight loss had significantly improved brachial artery macro-vascular flow-mediated vasodilation and micro-vascular reactive hyperemia. In contrast, vascular function did not change significantly in the lower insulin group (?12 uIU/mL) despite similar degree of weight loss.
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Report: Mazda Targets 700-pound Weight Reduction for Next Gen Miata
The reduction in fuel consumption for its models would mostly come from a reduction in weight for its next generation models and reduced dimensions of its vehicles (with a few rare exceptions, when a next generation of a vehicle is introduced, it is often larger and heavier than the model it replaces). Mazda is looking to remove an extraordinary amount of weight from the next generation MX-5 (better known as the Miata in North America). The NC (third generation) Miata isn’t exactly a pig, as it weighs 2,480 pounds with a 5-speed manual and 2,511 pounds with a 6-speed manual. However, this is over 300 pounds heavier than the NA (first generation) Miata which tipped the scales at 2,116 pounds. According to The Car Connection, Mazda’s current goal for the next generation Miata is to cut weight by 720 pounds. That would put a base Miata at just under 1,800 pounds — an almost unheard low for North American market vehicles.
For the original version including any supplementary images or video, visit http://www.dailytech.com/Report+Mazda+Targets+700pound+Weight+Reduction+for+Next+Gen+Miata/article21852.htm